Uvence has contributed to the development of the nanofat treatment by bringing standardisation and quality control to the process, with cryopreservation and delivery on demand. Please find further information via pre-selected articles featured on PubMed:

A 33-year-old woman with lower eyelid blepharochalasis and dark coloration of the lower eyelid skin extending into the nasojugal groove. (Right) Seven months after fat redraping, blepharoplasty, and intradermal injection of 1.6 cc nanofat in the lower eyelid and pigmented nasojugal groove.

1. Tonnard P, Verpaele A, Peeters G, Hamdi M, Cornelissen M, Declercq H. Nanofat grafting: basic research and clinical applications. Plast Reconstr Surg. 2013;132(4):1017-1026. doi: 10.1097/PRS.0b013e31829fe1b0

(A) Preoperative view of 29-year-old woman who underwent nanofat grafting and transconjunctival fat removal for correction dark low­er eyelids. (B) Postoperative 2-month view of the patient.

3. Oh DS, Kim DH, Roh TS, Yun IS, Kim YS. Correction of dark coloration of the lower eyelid skin with nanofat grafting. Arch Aesthetic Plast Surg. 2014;20(2):92-96. doi: 10.14730/aaps.2014.20.2.92

Patient before (left) and 10 months after (right) treatment for undereye dark circles with autologous fat in its different forms.

5. Ziade G, Karam D. Emulsified fat and nanofat for the treatment of dark circles. Dermatol Ther. 2020 Nov;33(6):e14100. doi: 10.1111/dth.14100

(A) Preoperative irregular patchy scar

(B) Postoperative irregular patchy scar

7. Banyard DA, Borad V, Liang LJ, et al. Use of condensed nanofat combined with fat grafts to treat atrophic scars. JAMA Facial Plast Surg. 2019;21(1):12-17. doi: 10.1001/jamafacial.2017.1329

A 24-year-old female patient with atrophic acne scars. (A) Before treatment. (B) Marked improvement after treatment with fractional CO2 laser and nanofat injection.

2. Rageh MA, El-Khalawany MA, Eltatawy RA, et al. Autologous nanofat injection combined with fractional CO₂ laser in the treatment of atrophic acne scars. Lasers Med Sci. 2020;35(4):873-881. doi: 10.1007/s10103-019-02899-9

(A) A 52-year-old female patient with a hyperpigmented, irregular skin lesion of the left cheek (B) Four months post-treatment.

4. Uyulmaz S, Macedo NS, Rezaeian F, Giovanoli P, Lindenblatt N. Nanofat grafting for scar treatment and skin quality improvement. Aesthet Surg J. 2018;38(4):421-428. doi: 10.1093/asj/sjx183

Clinical comparison before (A) and 2 years after temporal injection of Nanofat + PRP (B). Left side.

6. Pons O, Martín-Hernández C, Climent C, et al. Nanofat and platelet-rich plasma (PRP) in the treatment of inflammatory acne scars: a case report. J Stomatol Oral Maxillofac Surg. 2019;120(4):330-334. doi: https://doi.org/10.1016/j.jormas.2022.04.018

8. Fakih-Gomez G, García-Velasco A, Lázaro MJ, et al. Nanofat in facial rejuvenation: step-by-step procedure, patient evaluation, and recovery process. Am J Cosmet Surg. 2020;37(4):NP40-NP47. doi:10.1177/0748806820919935